Invenza Research

Des-[Gly]-31-Semaglutide (CAS No. NA), chemically known as (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,42S,45S,48S,51S,78S)-51-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-42-(3-amino-3-oxopropyl)-9-benzyl-36-(2-carboxyethyl)-18-(carboxymethyl)-30-(4-hydroxybenzyl)-6,12-bis((R)-1-hydroxyethyl)-15,24,27-tris(hydroxymethyl)-33-isobutyl-21-isopropyl-45,48-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,57,66,75,80-icosaoxo-59,62,68,71-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,56,65,74,79-icosaazahexanonacontane-1,78,96-tricarboxylic acid, is a well-characterized pharmaceutical impurity reference standard associated with Semaglutide. It is widely used by pharmaceutical research laboratories, analytical scientists, contract research organizations (CROs), and quality control laboratories to support impurity identification, chromatographic method development, analytical method validation, and stability studies.

This reference standard plays an important role in ensuring accurate impurity profiling during the development and quality assessment of Semaglutide-based pharmaceutical products. It is suitable for use in analytical techniques such as HPLC, LC-MS, UPLC, and other validated chromatographic methods where reliable impurity characterization is required.

Des-[Gly]-31-Semaglutide has the molecular formula C185H288N44O58 and a molecular weight of 4056.6 g/mol. It is also known by the chemical name (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,42S,45S,48S,51S,78S)-51-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-Indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanamido)-42-(3-amino-3-oxopropyl)-9-benzyl-36-(2-carboxyethyl)-18-(carboxymethyl)-30-(4-hydroxybenzyl)-6,12-bis((R)-1-hydroxyethyl)-15,24,27-tris(hydroxymethyl)-33-isobutyl-21-isopropyl-45,48-dimethyl-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,57,66,75,80-icosaoxo-59,62,68,71-tetraoxa-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,56,65,74,79-icosaazahexanonacontane-1,78,96-tricarboxylic acid and is identified by CAS No. NA.

Researchers and analytical laboratories utilize this impurity reference standard during pharmaceutical development, quality control testing, method transfer, and regulatory compliance activities. Its use helps support the characterization and monitoring of related substances throughout the product lifecycle.