Invenza Research

Atripla (CAS No. 731772-50-2), chemically known as fumaric acid compound with (R)-(((((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) and (S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one and 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one (1:1:1:1), is a well-characterized pharmaceutical impurity reference standard associated with Atripla. It is widely used by pharmaceutical research laboratories, analytical scientists, contract research organizations (CROs), and quality control laboratories to support impurity identification, chromatographic method development, analytical method validation, and stability studies.

This reference standard plays an important role in ensuring accurate impurity profiling during the development and quality assessment of Atripla-based pharmaceutical products. It is suitable for use in analytical techniques such as HPLC, LC-MS, UPLC, and other validated chromatographic methods where reliable impurity characterization is required.

Atripla has the molecular formula C14H9ClF3NO2 : C8H10FN3O3S : C19H30N5O10P : C4H4O4 and a molecular weight of 315.2 : 247.2 : 519.5 : 116.1 g/mol. It is also known by the chemical name fumaric acid compound with (R)-(((((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) and (S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one and 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one (1:1:1:1) and is identified by CAS No. 731772-50-2.

Researchers and analytical laboratories utilize this impurity reference standard during pharmaceutical development, quality control testing, method transfer, and regulatory compliance activities. Its use helps support the characterization and monitoring of related substances throughout the product lifecycle.